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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5D
All Species:
8.48
Human Site:
S55
Identified Species:
13.33
UniProt:
Q14738
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14738
NP_006236.1
602
69992
S55
A
Q
S
Q
P
P
S
S
N
K
R
P
S
N
S
Chimpanzee
Pan troglodytes
XP_518483
668
77639
S121
A
Q
S
Q
P
P
S
S
N
K
R
P
S
N
S
Rhesus Macaque
Macaca mulatta
XP_001087636
549
63874
G55
S
K
I
K
Y
S
G
G
P
Q
I
V
K
K
E
Dog
Lupus familis
XP_538927
602
69962
S55
P
Q
P
Q
P
P
S
S
N
K
R
P
S
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60996
524
60806
R31
P
V
A
L
L
H
I
R
D
V
P
P
A
D
Q
Rat
Rattus norvegicus
XP_001062510
563
65413
N54
S
S
N
K
R
P
S
N
S
T
P
P
P
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508677
454
52707
Chicken
Gallus gallus
XP_419321
459
53699
Frog
Xenopus laevis
NP_001087638
506
58853
K13
K
K
D
K
E
P
P
K
A
G
K
S
G
K
S
Zebra Danio
Brachydanio rerio
NP_998483
601
69849
L56
S
T
P
P
P
T
Q
L
N
K
I
K
Y
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138071
703
79051
K136
S
S
L
A
N
K
L
K
D
N
T
P
P
Y
D
Honey Bee
Apis mellifera
XP_392477
724
84384
Q55
L
I
N
K
I
K
Y
Q
P
G
G
P
I
I
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780420
579
66728
G53
L
T
R
T
K
G
T
G
P
L
V
K
K
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU89
510
58740
H17
P
N
K
K
S
S
K
H
E
H
R
G
R
E
H
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
D229
H
A
S
S
Q
S
I
D
I
P
R
S
S
H
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
91
98.8
N.A.
69.9
92
N.A.
70.2
72.5
69.7
85.2
N.A.
56.9
57.1
N.A.
68.2
Protein Similarity:
100
90.1
91.1
99.3
N.A.
78
92.8
N.A.
72.7
74.5
77.5
92.1
N.A.
68.8
67.4
N.A.
79
P-Site Identity:
100
100
0
86.6
N.A.
6.6
20
N.A.
0
0
13.3
20
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
26.6
86.6
N.A.
33.3
53.3
N.A.
0
0
33.3
33.3
N.A.
20
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.8
39.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.4
53.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
7
7
0
0
0
0
7
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
7
14
0
0
0
0
14
7
% D
% Glu:
0
0
0
0
7
0
0
0
7
0
0
0
0
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
7
14
0
14
7
7
7
0
7
% G
% His:
7
0
0
0
0
7
0
7
0
7
0
0
0
7
7
% H
% Ile:
0
7
7
0
7
0
14
0
7
0
14
0
7
7
0
% I
% Lys:
7
14
7
34
7
14
7
14
0
27
7
14
14
14
14
% K
% Leu:
14
0
7
7
7
0
7
7
0
7
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
14
0
7
0
0
7
27
7
0
0
0
20
0
% N
% Pro:
20
0
14
7
27
34
7
0
20
7
14
47
14
0
0
% P
% Gln:
0
20
0
20
7
0
7
7
0
7
0
0
0
0
14
% Q
% Arg:
0
0
7
0
7
0
0
7
0
0
34
0
7
0
0
% R
% Ser:
27
14
20
7
7
20
27
20
7
0
0
14
27
7
34
% S
% Thr:
0
14
0
7
0
7
7
0
0
7
7
0
0
7
0
% T
% Val:
0
7
0
0
0
0
0
0
0
7
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
7
0
0
0
0
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _